Medical City Dallas November 25, 2015

ABO Incompatible Transplant at Medical City Dallas

Thanksgiving 2015, our patient's wife gave him the gift of life by donating her kidney to him, even though they have different blood types.

Mark Justice, a Medical City patient, had been on a kidney transplant waiting list for the last four years anxiously anticipating that greatly desired call informing him that he finally has a donor.

The process of finding a matching donor for Mark has been especially long and difficult because he has blood type O – making him a universal donor for others but immensely limiting his options as a recipient. Having blood type O, Mark is only able to receive organ and blood transplants from donor with the same blood type – effectively eliminating all other donors with types A, B and AB.

Suffering from diabetes and already living with a permanent dialysis catheter to manage his impending kidney failure (a common condition among many people with blood type O), Mark’s timeline for survival and recovery hinged on finding a matching living donor through the paired kidney donor exchange program.

Unable to find a matching donor – even his wife was not a match – Mark and his physician, Dr. Mark Lerman, decided to pursue a non-matching blood type kidney transplant. The ABO Incompatible Transplant surgery, which has been performed at John Hopkins Hospital and Cedars Sinai, was the first of its kind to be successfully performed in the North Texas region. It involves eliminating the anti-B antibodies from the plasma in the donor’s blood and is administered to the transplant patient through a transfusion.


To learn more about ABO Incompatible Kidney Transplant Surgery at Medical City Dallas, click here.