|Location of Active Bone Marrow in an Adult|
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- Exposure to certain environmental toxins such as those found in gasoline, paint, oil and coal emissions, and industrial solvents
- High dose radiation and chemotherapy treatments
- Certain viruses
- Certain medications (eg, antibiotics, some illegal drugs, medications used to treat rheumatoid arthritis )
- Bone marrow diseases
- Shortness of breath with activity
- Rapid heart rate
- Pale skin
- Easy bruising
- Frequent infections
- Nosebleeds and bleeding gums
- Lengthy bleeding from cuts
- Skin rash
- Shortened attention span
- Blood test
- Bone marrow biopsy
Immune Suppressing Drugs
Bone Marrow Transplantation
Aplastic Anemia and MDS International Foundation http://www.aplastic.org
National Heart, Lung, and Blood Institute http://www.nhlbi.nih.gov
Aplastic Anemia and Myelodysplasia Association of Canada http://www.aamac.ca
The College of Family Physicians of Canada http://www.cfpc.ca
Ahn M, Choi J, Lee Y, et al. Outcome of adult severe or very severe aplastic anemia treated with immunosuppressive therapy compared with bone marrow transplantation: Multicenter trial. Int J Hematol . 2003;78:133-138.
Aplastic anemia. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. updated August 21, 2012. Accessed November 7, 2012.
Dokal I. Inherited aplastic anemia. Hematol J .2003; 4:3-9.
Locasciulli A. Acquired aplastic anemia in children: incidence, prognosis, and treatment options. Paediatr Drugs . 2002;4:761-766.
Loughran T Jr, Storb R. Treatment of aplastic anemia. Hematol Oncol Clin North Am . 1990;4:559-575.
Young NS. Acquired aplastic anemia. Ann Intern Med .2002;136:534-546.
- Reviewer: Kari Kassir, MD
- Review Date: 11/2012 -
- Update Date: 03/28/2013 -
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
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