Gastrointestinal Stromal Tumor
(GIST; Tumor, Gastrointestinal Stromal; Gastrointestinal Stromal Sarcoma; Gastric Myosarcoma; Gastric Myoblastoma; Gastrointestinal Leiomyosarcoma; Gastrointestinal Smooth Muscle Tumor)
|GIST may occur anywhere in the digestive system.|
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- Neurofibromatosis—a genetic disorder of the nervous system
- Family history of GIST—rare
- Tiredness and weakness
- Fever; sweating at night
- Weight loss
- Feeling full after eating a small amount of food
- Abdominal pain
- Painless lump in the abdomen
- Nausea and/or vomiting
- Blood in stool or vomit
- Problems swallowing
- Barium swallow
- Barium enema
- Computed tomography (CT) scan
- Magnetic resonance imaging (MRI) scan
- Positron emission tomography (PET) scan
American Cancer Society http://www.cancer.org
American Gastroenterological Association http://www.gastro.org
Canadian Association of Gastroenterology http://www.cag-acg.org
Canadian Cancer Society http://www.cancer.ca
Basu S, Balaji S, et al. Gastrointestional stromal tumors (GIST) and laparoscopic resection. Surg Endosc. 2007;21:1685-1689.
Huang HY, Li CF, et al. A modification of NIH consensus criteria to better distinguish the highly lethal subset of primary localized gastrointestinal stromal tumors: a subdivision of the original high-risk group on the basis of outcome. Surgery. 2007;141(6):748
Demetri GD, von Mehren M, et al. Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med. 2002;347(7):472.
Duffaud F, Blay J. Gastrointestinal stromal tumors: biology and treatment. Oncology. 2003;65:187-197.
Gastrointestinal stromal tumor. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated December 12, 2012. Accessed June 20, 2014.
Gastrointestinal stromal tumor. Ped Surg Update. 2005;24(6):3.
Gastrointestinal stromal tumor (GIST). American Cancer Society website. Available at: http://www.cancer.org/cancer/gastrointestinalstromaltumorgist/detailedguide/gastrointestinal-stromal-tumor-what-is-gist. Updated February 26, 2013. Accessed August 14, 2013.
Gastrointestinal stromal tumors (GISTs). Macmillan Cancer Support website. Available at: h http://www.macmillan.org.uk/Cancerinformation/Cancertypes/Softtissuesarcomas/Typesofsofttissuesarcomas/GIST.aspx. Updated January 1, 2013. Accessed August 14, 2013.
Rubin BP, Heinrich MC, et al. Gastrointestinal stromal tumour. Lancet. 2007;369(9574):1731-1741.
Shinomura Y, Kinoshita K, et al. Pathophysiology, diagnosis, and treatment of gastrointestinal stromal tumors. J Gastroenterol. 2005;40:775-780.
- Reviewer: Michael Woods, MD
- Review Date: 06/2014 -
- Update Date: 05/11/2013 -
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
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