(Hyaluronic Acid Injection; Injection, Hyaluronic Acid)
Reasons for Procedure
|Joints Affected by Osteoarthritis|
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- Pain and swelling
- Infection at the injection site
- Allergic reaction to the hyaluronic acid or local anesthetic product
- Inflammation of the blood vessels (vasculitis)
- Advanced OA
- Age 65 years and older
What to Expect
Prior to Procedure
- Pain medications
- Corticosteroid injections
- Physical therapy
- Weight loss
- Have x-rays done to determine the severity of your OA
- Ask you if you have any allergies to the ingredients in the hyaluronic acid product
Description of the Procedure
How Long Will It Take?
Will It Hurt?
- Apply ice to your knee to reduce swellng and pain.
- Avoid straining your knee for the first couple of days. Do not stand for a long time or do strenuous activity, like heavy lifting.
- Less knee pain
- Improved mobility
Call Your Doctor
- Signs of infection, including fever and chills
- Redness, swelling, increasing pain, bleeding, or discharge from the injection site
- Signs of allergic reaction
- Increased pain or swelling in the knee joint
American Chronic Pain Association http://www.theacpa.org
Ortho Info—American Academy of Orthopaedic Surgeons http://www.orthoinfo.org
Health Canada http://www.hc-sc.gc.ca
The Arthritis Society http://www.arthritis.ca
Arnold W, Fullerton D, et al. Viscosupplementation: managed care issues for osteoarthritis of the knee. Academy of Managed Care Pharmacy website. Available at: http://www.amcp.org/data/jmcp/May07%5Fsuppl.pdf. Accessed February 23, 2011.
Condon G. Putting a needle where it hurts. University of Connecticut Health Center website. Available at: http://today.uchc.edu/headlines/2005/may05/knees.html. Accessed February 23, 2011.
Degenerative joint disease of the knee. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated February 15, 2011. Accessed February 23, 2011.
Divine JG, Zazulak BT, et al. Viscosupplementation for knee osteoarthritis: A systematic review. Clin Orthop Relat Res. 2007;455:113-122.
Joint aspiration and injection. Cleveland Clinic website. Available at: http://my.clevelandclinic.org/services/services/hic%5Fjoint%5Faspiration%5Fand%5Finjection. Accessed February 24, 2011.
Viscosupplementation treatment for arthritis. American Academy of Orthopaedic Surgeons Ortho Info website. Available at: http://orthoinfo.aaos.org/topic.cfm?topic=a00217. Updated February 2009. Accessed February 23, 2011.
- Reviewer: Michael Woods, MD
- Review Date: 12/2014 -
- Update Date: 12/20/2014 -
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
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