HPV DNA Testing for Cervical Cancer Screening
The HPV Test
- Between the ages of 21-65 years
- Stopping in women over 65 years old with normal testing in the past 10 years
- Ages 21-29 years—Pap smear every 3 years without HPV testing
- Ages 30-65 years—Pap smear and HPV testing every 5 years or Pap smear alone every 3 years
Questions to Ask Your Doctor
- Am I a candidate for an HPV test as part of my cervical cancer screening program?
- Do you provide HPV testing as a follow-up to help clarify inconclusive Pap test results?
- If I have an inconclusive Pap test result, can you ask the lab to perform an automatic HPV test from the same Pap sample?
- Will my insurance cover the HPV test?
- Can I talk to you about questions I have about HPV and cervical cancer?
American Cancer Society http://www.cancer.org
National Cancer Institute http://www.cancer.gov
Canadian Cancer Society http://www.cancer.ca
Society of Obstetricians and Gynaecologists of Canada http://www.sogc.org
Cervical cancer. American Cancer Society website. Available at: http://www.cancer.org/acs/groups/cid/documents/webcontent/003042-pdf.pdf. Accessed February 10, 2015.
Cervical cancer screening. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated November 18, 2014. Accessed February 10, 2015.
Cuzick J. Human papillomavirus testing for primary cervical cancer screening. JAMA. 2000;283(1):108-109.
Human papillomavirus (HPV): Signs and symptoms. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/hpv/signs-symptoms.html. Updated January 22, 2015. Accessed February 10, 2015.
Human papillomavirus (HPV) vaccines. National Cancer Institute website. Available at: http://www.cancer.gov/cancertopics/factsheet/prevention/HPV-vaccine. Updated December 29, 2011. Accessed February 10, 2015.
Kulasingam SL, Hughes JP, et al. Evaluation of human papillomavirus testing in primary screening for cervical abnormalities. JAMA. 2002;288(14):1749-1757.
Making sense of your Pap and HPV test results. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/std/hpv/pap/default.htm. Updated July 25, 2012. Accessed February 10, 2015.
Manos MM, Kinney WK, et al. Identifying women with cervical neoplasia: Using human papillomavirus DNA testing for equivocal Papanicolaou results. JAMA. 199;281(17):1605-1610.
Pap and HPV testing. National Cancer Institute website. Available at: http://www.cancer.gov/cancertopics/factsheet/detection/Pap-HPV-testing. Updated September 9, 2014. Accessed February 10, 2015.
Schiffman M, Herrero R, et al. HPV DNA testing in cervical cancer screening: Results from women in a high-risk province of Costa Rica. JAMA. 2000;283(1):87-93.
Wright TC, Cox JT, et al. 2001 consensus guidelines for the management of women with cervical cytological abnormalities. JAMA. 2002;287:2120-2129.
Wright TC, Denny L, et al. HPV DNA testing of self-collected vaginal samples compared with cytologic screening to detect cervical cancer. JAMA. 2000;283(1):81-86.
- Reviewer: Michael Woods, MD
- Review Date: 02/2015 -
- Update Date: 02/10/2015 -
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
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