1 Ogasawara H, Middleton E Jr. Effect of selected flavonoids on histamine release (HR) and hydrogen peroxide (H2O2) generation by human leukocytes [abstract]. J Allergy Clin Immunol . 1985;75(suppl):184.
2 Middleton E Jr. Effect of flavonoids on basophil histamine release and other secretory systems. Prog Clin Biol Res. 1986;213:493-506.
3 Yoshimoto T, Furukawa M, Yamamoto S, et al. Flavonoids: potent inhibitors of arachidonate 5-lipoxygenase. Biochem Biophys Res Commun . 1983;116:612-618.
4 Shoskes DA, Zeitlin SI, Shahed A, et al. Quercetin in men with category III chronic prostatitis: a preliminary prospective, double-blind, placebo-controlled trial. Urology. 1999;54:960-963.
5 Rodriguez LV, Janzen N, Raz S, et al. Treatment of interstitial cystitis with a quercetin containing compound: a preliminary, double-blind placebo control trial. Presented at: American Urological Association 2001 Annual Meeting; June 2-7, 2001; Anaheim, CA.
6 Constant J. Alcohol, ischemic heart disease, and the French paradox. Coron Artery Dis . 1997;8:645-649.
7 Hayek T, Fuhrman B, Vaya J. Reduced progression of atherosclerosis in apolipoprotein E-deficient mice following consumption of red wine, or its polyphenols quercetin or catechin, is associated with reduced susceptibility of LDL to oxidation and aggregation. Arterioscler Thromb Vasc Biol . 1997;17:2744-2752.
8 Frankel EN, Waterhouse AL, Kinsella JE. Inhibition of human LDL oxidation by resveratrol. Lancet . 1993;341:1103-1104.
9 Alliangana DM. Effects of beta-carotene, flavonoid quercetin and quinacrine on cell proliferation and lipid peroxidation breakdown products in BHK-21 cells. East Afr Med J. 1996;73:752-757.
10 Keli SO, Hertog MG, Feskens EJ, et al. Dietary flavonoids, antioxidant vitamins, and incidence of stroke: the Zupthen study. Arch Intern Med. 1996;156:637-642.
11 Balasubramanian S, Govindasamy S. Inhibitory effect of dietary flavonol quercetin on 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis. Carcinogenesis. 1996;17:877-879.
12 Cross HJ, Tilby M, Chipman JK, et al. Effect of quercetin on the genotoxic potential of cisplatin. Int J Cancer . 1996;66:404-408.
13 Hoffman R, Graham L, Newlands ES. Enhanced anti-proliferative action of busulphan by quercetin on the human leukaemia cell line K562. Br J Cancer . 1989;59:347-348.
14 ElAttar TM, Virji AS. Modulating effect of resveratrol and quercetin on oral cancer cell growth and proliferation. Anticancer Drugs. 1999;10:187-193.
15 Yoshida M, Yamamoto M, Nikaido T. Quercetin arrests human leukemic T-cells in late G 1 phase of the cell cycle. Cancer Res. 1992;52:6676-6681.
16 Varma SD, Mizuno A, Kinoshita JH. Diabetic cataracts and flavonoids. Science . 1977;195:205-206.
17 Kaul TN, Middleton E Jr, Ogra PL. Antiviral effect of flavonoids on human viruses. J Med Virol . 1985;15:71-79.
18 Musci I, Pragai BM. Inhibition of virus multiplication and alteration of cyclic AMP level in cell cultures by flavonoids. Experientia . 1985;41:930-931.
19 Stavric B. Quercetin in our diet: from potent mutagen to probable anticarcinogen. Clin Biochem . 1994;27:245-248.
20 Friedman M, Smith GA. Factors which facilitate inactivation of quercetin mutagenicity. Adv Exp Med Biol . 1984;177:527-544.
21 ElAttar TM, Virji AS. Modulating effect of resveratrol and quercetin on oral cancer cell growth and proliferation. Anticancer Drugs. 1999;10:187-193.
22 Strick R, Strissel PL, Borgers S, et al. Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia. Proc Natl Acad Sci . 2000;97:4790-4795.
23 Weldin J, Jack R, Dugaw K, et al. Quercetin, an over-the-counter supplement, causes neuroblastoma-like elevation of plasma homovanillic acid. Pediatr Dev Pathol. 2004;6:547-551.
24 Lotito SB, Frei B. Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon? Free Radic Biol Med . 2006;41:1727-1746.
25 Edwards RL, Lyon T, Litwin SE, et al. Quercetin reduces blood pressure in hypertensive subjects. J Nutr. 2007;137:2405-2411.
- Reviewer: EBSCO CAM Review Board
- Review Date: 09/2014 -
- Update Date: 09/18/2014 -
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