What Is Nettle Used for Today?
What Is the Scientific Evidence for Nettle?
Interactions You Should Know About
- Anti-inflammatory, antihypertensive, sedative, or blood sugar-lowering medications: Nettle might conceivably interact with them, although this is unlikely.
1 Hryb DJ, Khan MS, Romas NA, et al. The effect of extracts of the roots of the stinging nettle ( Urtica dioica ) on the interaction of SHBG with its receptor on human prostatic membranes. Planta Med . 1995;61:31-32.
2 Wagner H, Willer F, Samtleben R, et al. Search for the antiprostatic principle of stinging nettle ( Urtica dioica ) roots. Phytomedicine. 1994;1:213-224.
3 Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physicians' Guide to Herbal Medicine . 3rd ed. Berlin, Germany: Springer-Verlag; 1998:229.
4 European Scientific Cooperative on Phytotherapy. Urticae radix . Exeter, UK: ESCOP, 1996-1997:2-4. Monographs on the Uses of Plant Drugs, Fascicule 2.
5 Konrad L, Muller HH, Lenz C, et al. Antiproliferative effect on human prostate cancer cells by a stinging nettle root ( Urtica dioica ) extract. Planta Med. 2000;66:44-47.
6 European Scientific Cooperative on Phytotherapy. Urticae radix . Exeter, UK: ESCOP, 1996-1997:4-5. Monographs on the Uses of Plant Drugs, Fascicule 2.
7 Vontobel HP, Herzog R, Rutishauser G, et al. Results of a double-blind study on the effectiveness of ERU (extractum radicis Urticae) capsules in conservative treatment of benign prostatic hyperplasia [translated from German]. Urologe A . 1985;24:49-51.
8 Dathe G, Schmid H. Phytotherapy of benign prostate hyperplasia (BPH); double-blind study with stinging nettle root extract (Extractum Radicis Urticae - ERU) [translated from German]. Urologe B . 1987;27:223-226.
9 European Scientific Cooperative on Phytotherapy. Urticae radix . Exeter, UK: ESCOP, 1996-1997:4. Monographs on the Uses of Plant Drugs, Fascicule 2.
10 Mittman P. Randomized, double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitis. Planta Med . 1990;56:44-47.
11 Randall C, Randall H, Dobbs F, et al. Randomized controlled trial of neetle sting for the treatment of base-of-thumb pain. J R Soc Med. 2000;93:305-309.
12 Hartmann RW, Mark M, Soldati F. Inhibition of 5 alpha-reductase and aromatase by PHL-00801 (Prostatonin), a combination of PY 102 (Pygeum africanum) and UR 102 (Urtica dioica) extracts. Phytomedicine. 1996;3:121-128.
13 Krzeski T, Kazon M, Borkowski A, et al. Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses. Clin Ther. 1993;15:1011-1020.
14 Sokeland J. Combined sabal and urtica extract compared with finasteride in men with benign prostatic hyperplasia: analysis of prostate volume and therapeutic outcome. BJU Int . 2000;86:439-442.
15 Marks LS, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol. 2000;163:1451-1456.
16 Shulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physicians' Guide to Herbal Medicine . 3rd ed. Berlin, Germany: Springer-Verlag; 1998:229.
17 Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-Care Professionals . London, England: Pharmaceutical Press; 1996:201-202.
18 Schottner M, Gansser D, Spiteller G. Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG). Planta Med . 1997;63:529-532.
19 Hirano T, Homma M, Oka K. Effects of stinging nettle root extracts and their steroidal components on the Na+,K(+)-ATPase of the benign prostatic hyperplasia. Planta Med . 1994;60:30-33.
20 Lichius JJ, Lenz C, Lindemann P, et al. Antiproliferative effect of a polysaccharide fraction of a 20% methanolic extract of stinging nettle roots upon epithelial cells of the human prostate (LNCaP). Pharmazie . 1999;54:768-771.
21 Safarinejad MR. Urtica dioica for treatment of benign prostatic hyperplasia: a prospective, randomized, double-blind, placebo-controlled, crossover study. J Herb Pharmacother . 2006;5:1-11.
22 Lopatkin N, Sivkov A, Walther C, et al. Long-term efficacy and safety of a combination of sabal and urtica extract for lower urinary tract symptoms a placebo-controlled, double-blind, multicenter trial. World J Urol. 2005 June 1. [Epub ahead of print]
- Reviewer: EBSCO CAM Review Board
- Review Date: 08/2013 -
- Update Date: 08/22/2013 -
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
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