What Is Melissa Used for Today?
What Is the Scientific Evidence for Lemon Balm?
1 Wolbling RH, Leonhardt K. Local therapy of herpes simplex with dried extract from Melissa officinalis . Phytomedicine . 1994;1:25-31.
2 Dimitrova Z, Dimov B, Manolova N, et al. Antiherpes effect of Melissa officinalis L. extracts. Acta Microbiol Bulg . 1993;29:65-72.
3 May G, Willuhn G. Antiviral effect of aqueous plant extracts in tissue culture [in German; English abstract]. Arzneimittelforschung . 1978;28:1-7.
4 Wolbling RH, Leonhardt K. Local therapy of herpes simplex with dried extract from Melissa officinalis . Phytomedicine . 1994;1:25-31.
5 Koytchev R, Alken RG, Dundarov S. Balm mint extract (Lo-701) for topical treatment of recurring Herpes labialis. Phytomedicine. 1999;6:225-230.
6 Soulimani R, Fleurentin J, Mortier F, et al. Neurotropic action of the hydroalcoholic extract of Melissa officinalis in the mouse. Planta Med . 1991;57:105-109.
7 Cerny A, Schmid K. Tolerability and efficacy of valerian/lemon balm in healthy volunteers (a double-blind, placebo-controlled, multicentre study). Fitoterapia. 1999;70:221-228.
8 Dressing H, Riemann D, Low H, et al. Insomnia: are valerian/balm combinations of equal value to benzodiazepine [translated from German]? Therapiewoche . 1992;42:726-736.
9 Wolbling RH, Leonhardt K. Local therapy of herpes simplex with dried extract from Melissa officinalis . Phytomedicine . 1994;1:25-31.
10 Soulimani R, Fleurentin J, Mortier F, et al. Neurotropic action of the hydroalcoholic extract of Melissa officinalis in the mouse. Planta Med . 1991;57:105-109.
11 Kennedy DO, Scholey AB, Tildesley NT, et al. Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm). Pharmacol Biochem Behav. 2002;72:953-964.
12 Ballard CG, O'Brien JT, Reichelt K, et al. Aromatherapy as a safe and effective treatment for the management of agitation in severe dementia: the results of a double-blind, placebo-controlled trial with Melissa. J Clin Psychiatry . 2002;63:553-558.
13 Akhondzadeh S, Noroozian M, Mohammadi M, et al. Melissa officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomised, placebo controlled trial. J Neurol NeurosurgPsychiatry . 2003;74:863-6.
14 Snow LA, Hovanec L, Brandt J. A Controlled trial of aromatherapy for agitation in nursing home patients with dementia. J Altern Complement Med . 2004;10:431-437.
15 Kennedy DO, Little W, Scholey AB. Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (lemon balm). Psychosom Med . 2004;66:607-613.
16 Kennedy DO, Little W, Haskell CF, Scholey AB. Anxiolytic effects of a combination of Melissa officinalis and Valeriana officinalis during laboratory induced stress. Phytother Res. 2006;20(2):96-102.
17 Savino F, Cresi F, Castagno E, Silvestro L, Oggero R. A randomized double-blind placebo-controlled trial of a standardized extract of Matricariae recutita, Foeniculum vulgare and Melissa officinalis (ColiMil) in the treatment of breastfed colicky infants. Phytother Res. 2005;19(4):335-340.
18 Vejdani R, Shalmani HR, Mir-Fattahi M, et al. The efficacy of an herbal medicine, Carmint, on the relief of abdominal pain and bloating in patients with irritable bowel syndrome: a pilot study. Dig Dis Sci. 2006;51(8):1501-1507.
As of 6/8/2011, additional research published on lemon balm does not warrant any changes to this article.
- Reviewer: EBSCO CAM Review Board
- Review Date: 07/2012 -
- Update Date: 07/25/2012 -
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