Principal Proposed Uses
What Is Ashwagandha Used for Today?
Interactions You Should Know About
1 Devi PU, Sharada AC, Solomon FE, et al. In vivo growth inhibitory effect of Withania somnifera (Ashwagandha) on a transplantable mouse tumour, Sarcoma 180. Indian J Exp Biol . 1992;30:169-172.
2 al-Hindawi MK, al-Khafaji SH, Abdul-Nabi MH. Anti-granuloma activity of Iraqi Withania somnifera . J Ethnopharmacol . 1992;37:113-116.
3 Kupparanjan K, et al. Effect of ashwaganda ( Withania somnifera Dunal) on the process of aging in human volunteers. J Res Ayurveda Siddha . 1980;1:247-258.
4 Bone K. [No title available]. MediHerb Professional Review . 1998;30.
5 Panda S, Kar A. Changes in thyroid hormone concentrations after administration of ashwagandha root extract to adult male mice. J Pharm Pharmacol. 1998;50:1065-1068.
6 Archana R, Namasivayam A. Antistressor effect of Withania somnifera.J Ethnopharmacol. 1999;64:91-93.
7 Dhuley JN. Therapeutic efficacy of ashwagandha against experimental aspergillosis in mice. Immunopharmacol Immunotoxicol. 1998;20:191-198.
8 Ziauddin M, Phansalkar N, Patki P, et al. Studies on the immunomodulatory effects of Ashwagandha. J Ethnopharmacol. 1996;50:69-76.
9 Dhuley JN. Effect of ashwagandha on lipid peroxidation in stress-induced animals. J Ethnopharmacol . 1998;60:173-178.
10 Singh N, Nath R, Lata A, et al. Withania somnifera (ashwagandha), a rejuvenating herbal drug which enhances survival during stress (an adaptogen). Int J Crude Drug Res . 1982;20:29-35.
11 Dadkar VN, Ranadive NU, Dhar HL. Evaluation of antistress (adaptogen) activity of Withania somnifera (ashwagandha). Indian J Clin Biochem . 1987;2:101-108.
12 Dhuley JN. Adaptogenic and cardioprotective action of ashwagandha in rats and frogs. J Ethnopharmacol . 2000;70:57-63.
13 Singh B, Saxena AK, Chandan BK, et al. Adaptogenic activity of a novel, withanolide-free aqueous fraction from the roots of Withania somnifera Dun. Phytother Res . 2001;15:311-318.
14 Davis L, Kuttan G. Effect of Withania somnifera on DMBA induced carcinogenesis. J Ethnopharmacol. 2001;75:165-168.
15 Prakash J, Gupta SK, Kochupillai V, et al. Chemopreventive activity of Withania somnifera in experimentally induced fibrosarcoma tumours in Swiss albino mice. Phytother Res . 2001;15:240-244.
16 Russo A, Izzo AA, Cardile V, et al. Indian medicinal plants as antiradicals and DNA cleavage protectors. Phytomedicine . 2001;8:125-132.
17 Singh DD, Dey CS, Bhutani KK. Downregulation of p34cdc2 expression with aqueous fraction from Withania somnifera for a possible molecular mechanism of anti-tumor and other pharmacological effects. Phytomedicine . 2001;8:492-494.
18 Gupta YK, Sharma SS, Rai K, et al. Reversal of paclitaxel induced neutropenia by Withania somnifera in mice. Indian J Physiol Pharmacol . 2001;45:253-257.
19 Dhuley JN. Nootropic-like effect of ashwagandha ( Withania somnifera L .) in mice. Phytother Res . 2001;15:524-528.
20 Jain S, Shukla SD, Sharma K, Bhatnagar M. Neuroprotective effects of Withania somnifera Dunn . in hippocampal sub-regions of female albino rat. Phytother Res . 2001;15:544-548.
21 Bhattacharya SK, Bhattacharya A, Sairam K, et al. Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study. Phytomedicine . 2000;7:463-469.
22 Ahmad MK, Mahdi AA, Shukla KK, et al. Withania somnifera improves semen quality by regulating reproductive hormone levels and oxidative stress in seminal plasma of infertile males. Fertil Steril. 2010;94(3):989-996.
23 Khanna D, Sethi G, Ahn KS, et al. Natural products as a gold mine for arthritis treatment. Curr Opin Pharmacol. 2007;7(3):344-351.
24 Winters M. Ancient medicine, modern use: Withania somnifera and its potential role in integrative oncology. Altern Med Rev. 2006;11(4):269-277.
25 Mishra LC, Singh BB, Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev. 2000;5(4):334-346.
As of 6/7/2011, additional research published on ashwagandha does not warrant any changes to this article.
- Reviewer: EBSCO CAM Review Board
- Review Date: 08/2013 -
- Update Date: 08/22/2013 -
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
Copyright © EBSCO Publishing
All rights reserved.