- Folate —Supplementation Possibly Helpful
- Other Nutrients —Supplementation Possibly Helpful
- St. John's Wort —Decreased Effectiveness of Drug
- Indole-3-Carbinol —Possible Decreased Effectiveness of Drug
- Dong Quai, St. John's Wort —Possible Harmful Interaction
- Rosemary —Possible Harmful Interaction
- Grapefruit Juice —Possible Harmful Interaction
- Resveratrol —Possible Harmful Interaction
- Milk Thistle —Possible Decreased Action of Drug
- Androstenedione —Theoretical Harmful Interaction
- Soy —Probably No Interaction
- Ortho Cyclen
- Ortho Tri-Cyclen
- and others
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13 Jobst KA, McIntyre M, St. George D, et al. Safety of St John's wort (Hypericum perforatum).Lancet 2000;355:575.
14 A to Z Drug Facts [book on CD-ROM]. 2nd ed. St. Louis, MO: Facts and Comparisons; 2000.
15 Takanaga H, Ohnishi A, Murakami H, et al. Relationship between time after intake of grapefruit juice and the effect on pharmacokinetics and pharmacodynamics of nisoldipine in healthy subjects. Clin Pharmacol Ther 2000;67:201-214.
16 Gehm BD, McAndrews JM, Chien PY, et al. Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor. Proc Natl Acad Sci U S A 1997;94:14138-14143.
17 Kim DH, et al. Silymarin and its components are inhibitors of beta-glucuronidase. Biol Pharm Bull 1994;17:443-445.
18 Leder BZ, Longcope C, Catlin DH, et al. Oral androstenedione administration and serum testosterone concentrations in young men. JAMA 2000;283:779-782.
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21 Michnovicz JJ. Increased estrogen 2-hydroxylation in obese women using oral indole-3-carbinol. Int J Obes Relat Metab Disord. 1998;22:227-229.
22 Bradlow HL, Sepkovic DW, Telang NT, et al. Multifunctional aspects of the action of indole-3-carbinol as an antitumor agent. Ann N Y Acad Sci. 1999;889:204-213.
23 Yuan F, Chen DZ, Liu K, et al. Anti-estrogenic activities of indole-3-carbinol in cervical cells: implication for prevention of cervical cancer. Anticancer Res. 1999;19:1673-1680.
24 Meng Q, Yuan F, Goldberg ID, et al. Indole-3-carbinol is a negative regulator of estrogen receptor-alpha signaling in human tumor cells. J Nutr. 2000;130:2927-2931.
25 Pfrunder A, Schiesser M, Gerber S, et al. Interaction of St John's wort with low-dose oral contraceptive therapy: a randomized controlled trial. Br J Clin Pharmacol . 2003;56:683-690.
26 Zhu BT, Loder DP, Cai MX, et al. Dietary administration of an extract from rosemary leaves enhances the liver microsomal metabolism of endogenous estrogens and decreases their uterotropic action in CD-1 mice. Carcinogenesis . 1998;19:1821-1827.
- Reviewer: EBSCO CAM Review Board
- Review Date: 08/2013 -
- Update Date: 08/22/2013 -
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