Medications for Type 1 Diabetes
|Insulin Injection Sites|
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|Type of insulin||Onset*||Peak time*||Duration*||Notes on use|
|Rapid-actingNovolog (aspart) Humalog (lispro) Apidra (glulisine)||10-30 minutes||0.5-3 hours||3-5 hours||Inject immediately before a meal.|
|Regular or short-actingNovolin R Humulin R||0.5-1 hour||2-5 hours||5-8 hours|
|1-2 hours||3-12 hours||18-24 hours||This is often used in combination with short-acting insulin.|
Insulin glargine (Lantus), Levemir (detemir)
|1 hour||n/a||24 hours||This may not be mixed with other types of insulin.|
|Type of insulin||Onset||Peak time||Duration|
|Humulin (50/50)||30 minutes||2-5 hours||18-24 hours|
|Humalog mix (75/25)||15 minutes||0.5-2.5 hours||16-20 hours|
|Humulin (70/30)||30 minutes||2-4 hours||14-24 hours|
|Novolin (70/30)||30 minutes||2-12 hours||up to 24 hours|
|Novolog Mix (70/30)||10-20 minutes||1-4 hours||up to 24 hours|
|Type of insulin||Brand names|
Humalog (insulin lispro)
NovoLog (insulin aspart)
*both require a prescription
|Regular or short-acting||
Humulin R (regular)
Humulin N (NPH)
Novolin N (NPH)
Lantus (insulin glargine)
- Check your insulin's expiration date. If you have not finished it before it expires, throw the rest away.
- Store unopened bottles of insulin in the refrigerator. Do not store your insulin at extreme temperatures.
- Keep the bottle of insulin you are using at room temperature. Injecting cold insulin can sometimes make the injection more painful. (Most doctors believe that insulin kept at room temperature will last 1 month. Check with the information on your glucose to make sure.)
- If your treatment requires that two different insulins be mixed, be sure that you understand which of the two should be drawn into the syringe first. If you change the mixing pattern, you may change the dose you receive. Some insulins cannot be mixed together. Do not mix insulins together in one syringe unless you have been instructed to do so.
American Diabetes Association. American Diabetes Association guidelines: standard of medical care in diabetes. Diabetes Care. 2006;29:S4-S42.
Amylin agonists: a novel approach in the treatment of diabetes. Diabetes. 2004; 53(Supp 3):S233-238.
Diabetes causes. National Institute of Diabetes & Digestive & Kidney Diseases website. Available at: http://diabetes.niddk.nih.gov/dm/pubs/causes/index.aspx. Accessed December 31, 2012.
Diabetes type 1. EBSCO DynaMed website. Available at: https://dynamed.ebscohost.com/about/about-us. Updated December 28, 2012. Accessed December 31, 2012.
McMahon GT, Arky RA. Inhaled insulin for diabetes mellitus. N Engl J Med. 2007;356:497-502
Traina AN, Kane MP. Primer on pramlintide, an amylin analog. Diabetes Educ. 2011;37(3):426-431.
Type 1 diabetes. American Diabetes Association website. Available at: http://www.diabetes.org/diabetes-basics/type-1/?loc=DropDownDB-type1. Accessed December 31, 2012.
9/23/2008 DynaMed's Systematic Literature Surveillance. http://www.ebscohost.com/dynamed/what.php: The Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Study Group. Continuous glucose monitoring and intensive treatment of type 1 diabetes. N Engl J Med. 2008 Sep 8. [Epub ahead of print]
- Reviewer: Kim Carmichael, MD
- Review Date: 09/2013 -
- Update Date: 09/30/2013 -
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
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