Conditions InDepth: Peripheral Artery Disease (PAD)
- Smoking—chemicals from cigarette smoke can irritate blood vessel walls and make deposits in the walls of blood vessels
- High cholesterol—"bad" cholesterol can stick to and irritate the walls of the blood vessels
- High blood pressure—causes turbulent blood flow that can injure the walls of blood vessels
- Diabetes—excess glucose in the blood can contribute to plaque build up in blood vessels
- Radiation therapy
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About peripheral artery disease (PAD). American Heart Association website. Available at: http://www.heart.org/HEARTORG/Conditions/More/PeripheralArteryDisease/About-Peripheral-Artery-Disease-PAD%5FUCM%5F301301%5FArticle.jsp. Updated September 13, 2012. Accessed June 20, 2014.
Hills AJ, Shalhoub J, et al. Peripheral arterial disease. Br J Hosp Med (Lond). 2009;70(10):560-565.
Jurado JA, Bashir R, et al. Radiation-induced peripheral artery disease. Catheter Cardiovasc Interv. 2008;72(4):563-568.
Peripheral arterial disease (PAD) of lower extremities. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated June 13, 2014. Accessed June 20, 2014.
What causes peripheral arterial disease? National Heart, Lung, and Blood Institute website. Available at: http://www.nhlbi.nih.gov/health/health-topics/topics/pad/causes.html. Updated June 2, 2014. Accessed June 20, 2014.
What is peripheral arterial disease? National Heart, Lung, and Blood Institute website. Available at: http://www.nhlbi.nih.gov/health/health-topics/topics/pad. Updated June 2, 2014. Accessed June 20, 2014.
- Reviewer: Michael J. Fucci, DO; Brian Randall, MD
- Review Date: 08/2013 -
- Update Date: 00/62/2014 -
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
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