(Arthritis, Gouty; Gouty Arthritis)
- Too much uric acid is produced
- Not enough uric acid is eliminated
- Obesity , sudden weight gain, or rapid weight loss
- Family members with history of gout
- Kidney disease
- Diabetes mellitus
- High blood pressure
- Certain types of cancer
Certain medications, such as:
- Low-dose aspirin
- Cyclosporin, an antirejection drug
- Chemotherapy drugs used to treat cancer
- Foods high in purines, such as organ meats, shellfish, some vegetables, and gravies
- High-fructose drinks, such as sugar-sweetened sodas and orange juice
- Excess alcohol , especially beer
- Sudden onset of severe pain in an inflamed joint, usually starting in the big toe
- Joints that are red, hot, swollen, and tender
- Increased pain 24-48 hours after the onset of symptoms
|Gout of the Big Toe|
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- Kidney stones
- Kidney disease
- Joint destruction
- A sample of fluid taken from the affected joint
- Blood tests
- Urine tests
- The number of joints affected
- Previous responses to treatment
- Overall health
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Corticosteroids—may be given orally or as an injection into the affected joint
- A low purine diet
- Alcohol avoidance
- Gradual weight loss in those who are obese
- Stopping or changing medications that may be causing recurrent gout
- Increasing fluid intake
- To lower the production of uric acid
- To increase the excretion of uric acid by the kidneys
- To convert uric acid into a different byproduct
- Eat a low-purine diet.
- Limit how much alcohol you drink. Avoid binge drinking.
- Drink a lot of fluids.
- Lose weight gradually.
American Arthritis Society http://www.americanarthritis.org
Arthritis Foundation http://www.arthritis.org
Arthritis Society of Canada http://www.arthritis.ca
Canadian Arthritis Network http://www.arthritisnetwork.ca
Gout. American College of Rheumatology website. Available at: http://www.rheumatology.org/Practice/Clinical/Patients/Diseases%5FAnd%5FConditions/Gout. Updated September 2012. Accessed June 29, 2015.
Gout. Arthritis Foundation website. Available at: http://www.arthritis.org/about-arthritis/types/gout/. Accessed June 29, 2015.
Gout. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated January 21, 2015. Accessed June 29, 2015.
Gout - treatment of acute attack. Available at: http://www.ebscohost.com/dynamed. Updated October 13, 2014. Accessed June 29, 2015.
Gout overview. American Academy of Family Physicians Family Doctor website. Available at: http://familydoctor.org/familydoctor/en/diseases-conditions/gout.html. Updated July 2013. Accessed June 29, 2015.
Questions and answers about gout. National Institute of Arthritis and Musculoskeletal and Skin Diseases website. Available at: http://www.niams.nih.gov/Health%5FInfo/Gout/default.asp. Updated April 2012. Accessed June 29, 2015.
Rott KT, Agudelo CA. Gout. JAMA. 2003;289:2857-2860.
Terkeltaub RA. Clinical practice. Gout. N Engl J Med. 2003;349:1647-1655.
What is gout? National Institute of Arthritis and Musculoskeletal and Skin Diseases website. Available at: http://www.niams.nih.gov/Health%5FInfo/Gout/gout%5Fff.pdf. Published November 2014. Accessed June 29, 2015.
1/4/2011 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed: Man CY, Cheung IT, Cameron PA, Rainer TH. Comparison of oral prednisolone/paracetamol and oral indomethacin/paracetamol combination therapy in the treatment of acute gout-like arthritis: a double-blind, randomized, controlled trial. Ann Emerg Med. 2007;49:670-677. Epub 2007 Feb 5.
1/4/2011 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed: Choi HK, Willett W, Curhan G. Fructose-rich beverages and risk of gout in women. JAMA. 2010;304(20):2270-2278.
4/24/2014 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed: Wise JN, Weissman BN, et al. American College of Radiology (ACR) Appropriateness Criteria for chronic foot pain. Available at: http://www.acr.org/~/media/ACR/Documents/AppCriteria/Diagnostic/ChronicFootPain.pdf. Updated 2013. Accessed June 29, 2015.
- Reviewer: Michael Woods, MD
- Review Date: 06/2015 -
- Update Date: 04/24/2014 -
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
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