|Pathway of Pulmonary Embolism|
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- Blood clot in a deep vein of a leg or the pelvis
- Increased levels of clotting factors in the blood
- Prolonged bed rest
- Major surgery, especially after pelvic surgery, knee replacement, or heart surgery
- Injury to a vein in a leg or the pelvis
- Fractures of the hip or thigh bone
- Certain blood disorders
- Prolonged sitting, such as during a long trip
- Pregnancy or postpartum period
- Inflammatory bowel disease
- Autoimmune disorder, such as immune thrombocytopenic purpura, polyarteritis nodosa, or polymyositis
- Taking certain medications, such as birth control pills or antipsychotics
- Arterial blood gas study—to check oxygen levels and lung function
- Electrocardiogram (EKG)—to assess the electrical activity of the heart
- D-Dimer blood test—to detect the presence of a clot
If you have a family history of blood clots, and had blood clots in the past for no apparent reason, your doctor may do additional blood tests. The tests will look for possible inherited defects in your clotting system, such as:
- Factor V Leiden mutation (seen in up to 40% of cases)
- Increased factor VIII
- Eat a healthful diet that is low in saturated fat and rich in whole grains, fruits, and vegetables.
- Begin a safe exercise program with the advice of your doctor.
- Walk or move your legs to break up long periods of sitting.
- If you smoke, talk with your doctor on ways you can quit.
- Unless you are on a fluid-restricted diet, be sure to drink lots of water.
- Take medication if your doctor recommends it. Anticoagulant drugs are most commonly used.
- Wear elastic stockings if suggested by your doctor. They can help improve circulation in your legs.
- Walk or move your legs to break up long periods of sitting. If you are traveling, get up and walk every few hours.
American Lung Association http://www.lung.org
American Society of Hematology http://www.hematology.org
Health Canada http://www.hc-sc.gc.ca
The Lung Association http://www.lung.ca
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Pulmonary embolism. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated September 11, 2014. Accessed September 26, 2014.
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Rubini G, Niccoli A, et al. Acute pulmonary embolism: comparison and integration of perfusion lung scintigraphy with multislice spiral CT. Radiol Med. 2007;112:174-184.
10/5/2010 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed: Parker C, Coupland C, Hippisley-Cox J. Antipsychotic drugs and risk of venous thromboembolism: nested case-control study. BMJ. 2010;341:c4245.
12/17/2010 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed: Grainge MJ, West J, Card TR. Venous thromboembolism during active disease and remission in inflammatory bowel disease: a cohort study. Lancet. 2010;375(9715):657-663.
1/26/2012 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed: Zöller B, Li X, Sundquist J, Sundquist K. Risk of pulmonary embolism in patients with autoimmune disorders: a nationwide follow-up study from Sweden. Lancet. 2012;379(9812):244-249.
- Reviewer: Michael Woods, MD
- Review Date: 08/2014 -
- Update Date: 09/30/2013 -
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
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