|Vaccination and Lymph System|
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- Through the airborne droplets of infected saliva
- Between people who have direct contact
- Through the handling of contaminated bed linens or clothing
- High fever
- Severe headache
- Stomach pain
- Sore throat
- Nausea and vomiting
- Rash appears on the mouth, throat, face, and arms, then spreads to the legs and trunk
- Red, flat lesions
- Lesions appear at the same time
- Lesions fill with fluid, then pus
- Crusts form during the second week
- Scabs form and fall off after 3-4 weeks
- High fever
- Possible stomach pain
- Dark red coloration
- Bleeding into the skin and mucus membranes
- High fever
- Slowly developing lesions that remain soft and flat
- Skin looks like reddish-colored crepe rubber
- Large amounts of skin may peel, if the patient survives
- Examination of saliva and fluid from skin lesions under a microscope
- Taking a sample (a culture) of saliva and fluid from skin lesions
- Blood test to detect antibodies to smallpox
Public Health Measures
- Be vaccinated
- Wear a mask, gloves, goggles, and a gown
- Disinfect clothing, bed linens, and surfaces
Centers for Disease Control and Prevention http://www.cdc.gov
National Library of Medicine http://www.nlm.nih.gov
Health Canada http://www.hc-sc.gc.ca
Public Health Agency of Canada http://www.phac-aspc.gc.ca
Breman JG, Henderson DA. Diagnosis and management of smallpox. N Engl J Med. 2002;25;346:1300-1308.
Dambro MR. Griffith's 5-Minute Clinical Consult. Philadelphia, PA: Lippincott Williams & Wilkins; 2001.
Mandell GL, Bennett JE, et al. Principles and Practice of Infectious Diseases. 6th ed. United Kingdom: Churchill Livingstone, Inc; 2004.
Smallpox. World Health Organization website. Available at: http://www.who.int/csr/disease/smallpox/faq/en/index.html.
Working Group on Civilian Biodefense. Smallpox as a biological weapon: medical and public health management. JAMA. 1999;281:2127-2137.
- Reviewer: Michael Woods, MD
- Review Date: 06/2013 -
- Update Date: 06/20/2013 -
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