|Vaccination and Lymph System|
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- Through the airborne droplets of infected saliva
- Between people who have direct contact
- Through the handling of contaminated bed linens or clothing
- High fever
- Severe headache
- Stomach pain
- Sore throat
- Nausea and vomiting
- Rash appears on the mouth, throat, face, and arms, then spreads to the legs and trunk
- Red, flat lesions
- Lesions appear at the same time
- Lesions fill with fluid, then pus
- Crusts form during the second week
- Scabs form and fall off after 3-4 weeks
- High fever
- Possible stomach pain
- Dark red coloration
- Bleeding into the skin and mucus membranes
- High fever
- Slowly developing lesions that remain soft and flat
- Skin looks like reddish-colored crepe rubber
- Large amounts of skin may peel, if the patient survives
- Examination of saliva and fluid from skin lesions under a microscope
- Taking a sample (a culture) of saliva and fluid from skin lesions
- Blood test to detect antibodies to smallpox
Public Health Measures
- Be vaccinated
- Wear a mask, gloves, goggles, and a gown
- Disinfect clothing, bed linens, and surfaces
Centers for Disease Control and Prevention http://www.cdc.gov
National Institute of Allergy and Infectious Diseases http://www.niaid.nih.gov
Health Canada http://www.hc-sc.gc.ca
Public Health Agency of Canada http://www.phac-aspc.gc.ca
Breman JG, Henderson DA. Diagnosis and management of smallpox. N Engl J Med. 2002;25;346:1300-1308.
Frequently asked questions and anwers on smallpox. World Health Organization website. Available at: http://www.who.int/csr/disease/smallpox/faq/en. Accessed January 16, 2015.
Smallpox. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Accessed January 16, 2015.
Smallpox. University of Minnesota Center for Infectious Disease Research and Policy website. Available at: http://www.cidrap.umn.edu/infectious-disease-topics/smallpox. Updated February 24, 2014. Accessed January 16, 2015.
Working Group on Civilian Biodefense. Smallpox as a biological weapon: medical and public health management. JAMA. 1999;281:2127-2137.
- Reviewer: Fabienne Daguilh, MD
- Review Date: 01/2015 -
- Update Date: 08/27/2014 -
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
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