|Pathway to the Lungs|
|Mycobacterium tuberculosis is inhaled through the mouth and nose and travels down into the lungs causing TB.|
|Copyright © Nucleus Medical Media, Inc.|
- Weakened immune system or chronic diseases (highest risk)
- HIV infection
- Intravenous drug use
- Leukemia , lymphoma , and other cancers
- Poorly controlled diabetes
- Severe kidney disease
- Medications that lower the immune system response such as those use to treat rheumatoid arthritis
- Suppressed immune system caused by medicines, such as drugs to prevent rejection of a transplanted organ
- Smoking habit
- Silicosis (an occupational lung disease)
- Living in crowded, indoor conditions (eg, homeless shelters, dormitories, military barracks)
- Age (infants, young children, and elderly people are more susceptible)
- Severe cough that lasts more than two weeks
- Coughing up blood and mucus from deep in the lungs
- Pain in the chest
- Weakness or fatigue
- Unexplained weight loss
- Night sweats
- Loss of appetite
- Chest x-ray
- Samples of your sputum —to be tested for the bacterium
For Inactive TB
For Active TB
American Lung Association http://www.lungusa.org/
National Institute of Allergy and Infectious Disease http://www.niaid.nih.gov/
The Canadian Lung Association http://www.lung.ca/
Health Canada http://www.hc-sc.gc.ca/
Division of Tuberculosis Elimination. Centers for Disease Control website. Available at: http://www.cdc.gov/tb/topic/basics/default.htm . Updated March 13, 2012. Accessed December 28, 2012.
Hawkridge T, Mahomed H. Prospects for a new, safer and more effective TB vaccine. Paediatr Respir Rev . 2011 Mar;12(1):46-51.
Active Tuberculosis. EBSCO DynaMed website. Available at: https://dynamed.ebscohost.com/about/about-us . Updated December 7, 2012. Accessed December 28, 2012.
Latent Tuberculosis. EBSCO DynaMed website. Available at: https://dynamed.ebscohost.com/about/about-us . Updated October 29, 2012. Accessed December 28, 2012.
Updated Guidelines for Using Interferon Gamma Release Assays to Detect Mycobacterium tuberculosis Infection—United States, 2010. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5905a1.htm . Published June 2010. Accessed December 28, 2012.
12/16/2011 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed/what.php : Sterling T, Villarino E, Borisov A, et al. Three months of rifapentine and isoniazid for latent tuberculosis infection. N Engl J Med. 2011;365(23):2155.
- Reviewer: Michael Woods, MD
- Review Date: 11/2012 -
- Update Date: 11/26/2012 -
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
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