What is the Scientific Evidence for Strontium?
Interactions You Should Know About
1 Reginster JY, Seeman E, DE Vernejoul MC, et al. Strontium ranelate reduces the risk of invertebral fractures in postmenopausal women with osteoporosis: Treatment of Perpheral Osteoporosis (TROPOS) study. J Clin Endocrinol Metab . 2005 Feb 22 [Epub ahead of print].
2 Reginster JY, Meunier PJ. Strontium ranelate phase 2 dose-ranging studies: PREVOS and STRATOS studies. Osteoporos Int . 2003. [Epub ahead of print].
3 Reginster JY, Deroisy R, Jupsin I. Strontium ranelate: a new paradigm in the treatment of osteoporosis. DrugsToday (Barc) . 2003;39:89–101.
4 Reginster JY, Deroisy R, Dougados M, Jupsin I, Colette J, Roux C. Prevention of early postmenopausal bone loss by strontium ranelate: the randomized, two-year, double-masked, dose-ranging, placebo-controlled PREVOS trial. Osteoporos Int . 2002;13:925–31.
5 Meunier PJ, Slosman DO, Delmas PD, et al. Strontium ranelate: dose-dependent effects in established postmenopausal vertebral osteoporosis—a 2-year randomized placebo controlled trial. J Clin Endocrinol Metab . 2002;87:2060–6.
6 Meunier PJ, Roux C, Seeman E, et al. The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. N Engl J Med . 2004;350:459–68.
7 Brandi ML. New treatment strategies: ipriflavone, strontium, vitamin D metabolites and analogs. Am J Med . 1993;95:69S–74S.
8 Matsumoto A. Effect of strontium chloride on bone resorption induced by prostaglandin E2 in cultured bone. ArchToxicol . 1988;62:240–1.
9 Marie PJ, Hott M. Short-term effects of fluoride and strontium on bone formation and resorption in the mouse. Metabolism . 1986;35:547–51.
10 Marie PJ, Garba MT, Hott M, Miravet L. Effect of low doses of stable strontium on bone metabolism in rats. Miner Electrolyte Metab . 1985;11:5–13.
11 Brandi ML. New treatment strategies: ipriflavone, strontium, vitamin D metabolites and analogs. Am J Med . 1993;95:69S–74S
12 Ferraro EF, Carr R, Zimmerman K. A comparison of the effects of strontium chloride and calcium chloride on alveolar bone. Calcif Tissue Int . 1983;35:258–60.
13 Ferraro EF, Glass RT. The effect of strontium chloride upon alveolar bone. J Periodontol . 1980;51:345–7.
14 Marie PJ. Strontium ranelate: a dual mode of action rebalancing bone turnover in favour of bone formation. Curr Opin Rheumatol. 2006;18 Suppl 1:S11-5.
15 O'donnell S, Cranney A, Wells G, et al. Strontium ranelate for preventing and treating postmenopausal osteoporosis. Cochrane Database Syst Rev. 2006;:CD005326.
16 Halil M, Cankurtaran M, Yavuz BB, et al. Short-Term Hemostatic Safety of Strontium Ranelate Treatment in Elderly Women with Osteoporosis. Ann Pharmacother. 2007;41:41-5.
- Reviewer: EBSCO CAM Review Board
- Review Date: 09/2014 -
- Update Date: 09/18/2014 -
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