Principal Proposed Uses
What Is Saffron Used for Today?
1 Akhondzadeh S, Tahmacebi-Pour N, Noorbala AA, et al. Crocus sativus L. in the treatment of mild to moderate depression: a double-blind, randomized and placebo-controlled trial. Phytother Res . 2005;19:148–51.
2 Noorbala AA, Akhondzadeh S, Tahmacebi-Pour N, et al. Hydro-alcoholic extract of Crocus sativus L. versus fluoxetine in the treatment of mild to moderate depression: a double-blind, randomized pilot trial. J Ethnopharmacol . 2005;97:281–4.
3 Akhondzadeh S, Fallah-Pour H, Afkham K, et al. Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double-blind randomized trial [ISRCTN45683816]. BMCComplement Altern Med . 2004;4:12.
4 Abdullaev Jafarova F, Caballero-Ortega H, Riveron-Negrete L, et al. In vitro evaluation of the chemopreventive potential of saffron [in Spanish]. Rev Invest Clin . 2003;54:430–6.
5 Escribano J, Alonso GL, Coca-Prados M, et al. Crocin, safranal and picrocrocin from saffron ( Crocus sativus L.) inhibit the growth of human cancer cells in vitro. Cancer Lett . 1996;100:23–30.
6 Abdullaev FI, Espinosa-Aguirre JJ. Biomedical properties of saffron and its potential use in cancer therapy and chemoprevention trials. Cancer Detect Prev . 2004;28:426–32.
7 Molnar J, Szabo D, Pusztai R, et al. Membrane associated antitumor effects of crocine-, ginsenoside- and cannabinoid derivates. Anticancer Res . 2000;20:861–7.
8 Abdullaev FI, Riveron-Negrete L, Caballero-Ortega H, et al. Use of in vitro assays to assess the potential antigenotoxic and cytotoxic effects of saffron ( Crocus sativus L.). Toxicol In Vitro . 2003;17:731–6.
9 Garcia-Olmo DC, Riese HH, Escribano J, et al. Effects of long-term treatment of colon adenocarcinoma with crocin, a carotenoid from saffron ( Crocus sativus L.): an experimental study in the rat. Nutr Cancer . 2000;35:120–6.
10 Xu GL, Yu SQ, Gong ZN, et al. Study of the effect of crocin on rat experimental hyperlipemia and the underlying mechanisms [in Chinese]. Zhongguo Zhong Yao Za Zhi . 2005;30:369–72.
11 el Daly ES. Protective effect of cysteine and vitamin E, Crocus sativus and Nigella sativa extracts on cisplatin-induced toxicity in rats. J Pharm Belg . 1998;53:87–93.
12 Abe K, Saito H. Effects of saffron extract and its constituent crocin on learning behaviour and long-term potentiation. Phytother Res . 2000;14:149–52.
13 Noorbala AA, Akhondzadeh S, Tahmacebi-Pour N, et al. Hydro-alcoholic extract of Crocus sativus L. versus fluoxetine in the treatment of mild to moderate depression: a double-blind, randomized pilot trial. J Ethnopharmacol . 2005;97:281–4.
14 Moshiri E, Basti AA, Noorbala AA et al. Crocus sativus L. (petal) in the treatment of mild-to-moderate depression: A double-blind, randomized and placebo-controlled trial. Phytomedicine . 2006 Sep 14 [Epub ahead of print]
15 Akhondzadeh Basti A, Moshiri E, Noorbala AA, et al. Comparison of petal of Crocus sativus L and fluoxetine in the treatment of depressed outpatients: a pilot double-blind randomized trial. Prog Neuropsychopharmacol Biol Psychiatry . 2006 Dec 14 [Epub ahead of print].
16 Modaghegh MH, Shahabian M, Esmaeili HA, et al. Safety evaluation of saffron ( Crocus sativus ) tablets in healthy volunteers. Phytomedicine. 2008 Aug 5.
- Reviewer: EBSCO CAM Review Board
- Review Date: 08/2013 -
- Update Date: 08/22/2013 -
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