|The Thyroid Gland|
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- Medication during pregnancy, such as radioactive iodine therapy
- Maternal autoimmune disease
- Too much iodine during pregnancy
- Inborn error of metabolism
- Puffy face
- Coarse facial features
- Dull look
- Thick protruding tongue
- Poor feeding
- Choking episodes
- Constipation or reduced stooling
- Yellow skin color— jaundice
- Short stature
- Swollen abdomen
- Decreased activity
- Sleeps a lot
- Rarely cries or hoarse cry
- Dry brittle hair; low hairline
- Poor muscle tone
- Cool and pale skin
- Poor weight gain due to poor appetite
- Poor growth
- Difficult breathing
- Low temperature
- Swollen hands, feet and genitals
- Thyroid scan (technetium)
- Nuclear imaging (scintigraphy)
- Avoid radioactive iodine treatment or iodine as antiseptic during pregnancy
- Consume enough, but not too much iodine during pregnancy
American Thyroid Association http://www.thyroid.org
Genetics Home Reference http://ghr.nlm.nih.gov
Health Canada http://www.hc-sc.gc.ca
Thyroid Foundation of Canada http://www.thyroid.ca
Bongers-Schokking JJ, Koot HM, et al. Influence of timing and dose of thyroid hormone replacement on the development in infants with congenital hypothyroidism. J Ped. 2000;136:292-297.
Castanet M, Polak M, et al. Familial forms of thyroid dysgenesis. Endocr Dev. 2007;10:15-28.
Congenital hypothyroidism. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated November 3, 2014. Accessed December 11, 2014.
Gruters A, Krude H, Biebermann H. Molecular genetic defects in congenital hypothyroidism. Europ J Endocr. 2004;151:39-44.
LeFranchi SH, Austin J. How should we be treating children with congenital hypothyroidism. J Pediatr Endocrinol Metab. 2007;20:559-578.
Update of newborn screening and therapy for congenital hypothyroidism. American Academy of Pediatrics. Pediatrics. 2006;117:2290-2303.
- Reviewer: Kim A. Carmichael, MD, FACP
- Review Date: 12/2014 -
- Update Date: 12/20/2014 -
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
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