(Calcium Pyrophosphate Deposition Disease; Calcium Pyrophosphate Dihydrate Crystal Deposition Disease; Chondrocalcinosis)
|Arthritis of the Knee|
|Copyright © Nucleus Medical Media, Inc.|
- Risk increases with age
- Attacks may occur more often and may become more severe with age
- Family members with pseudogout
- Hypothyroidism —an underactive thyroid
- Hemochromatosis —excess iron storage
- Overactive parathyroid gland—one of four endocrine glands situated above or within the thyroid gland that increases the calcium level in the blood
- Hypercalcemia—a condition of too much calcium in the blood
- Kidney failure
- Recent surgery—pseudogout sometimes develops after surgery
- Injury—injury to the joint, especially in older people, can trigger release of the calcium crystals
Pain or tenderness in joints
- Pain feels like an attack of arthritis
- Very sensitive to pressure
- Stiffness in joints
- Swollen joints that are warm to the touch
- Redness of skin around the joint
- Joint aspiration—Your doctor may use a needle to remove some of the fluid around the affected joint to determine if the crystals in the fluid are calcium pyrophosphate crystals
- X-ray—Your doctor may also take an x-ray of the affected joint or joints to determine whether calcium crystals are present
- Blood tests—These tests are used to rule out other conditions, such as gout, rheumatoid arthritis, or osteoarthritis, that may be the cause of the swelling and pain in the joints
- Anti-inflammatory medications—(eg, aspirin) are administered to decrease inflammation.
- Nonsteroidal anti-inflammatory drugs (NSAIDs)—(eg, ibuprofen, naproxen, indomethacin) are given to stop painful attacks quickly and to reduce inflammation.
- Corticosteroids—used to decrease inflammation. They may be injected into the affected joint or given as pills.
- Colchicine—another type of anti-inflammatory medicine. Studies have found that colchicine can be used to prevent further attacks.
|Steroids Injected into Joint|
|Copyright © Nucleus Medical Media, Inc.|
- Cortisone shots—Your doctor may choose to give you a cortisone shot into the affected joint. Cortisone is a powerful anti-inflammatory medication. It is a synthetic (man-made) version of a type of steroid that is produced naturally by a gland in your body called the adrenal gland.
- Arthrocentesis—This procedure involves removal of fluid and crystals from the joint through a needle. Removal of the fluid may give you some relief from the pain.
- Surgery—sometimes done to repair or replace any damaged joints.
- Talk to your doctor about taking an anti-inflammatory medication to prevent the symptoms
Protect your joints–don’t put extra stress on your joints
- Avoid lifting heavy items
- Lift and carry things properly, using your back, arms, and legs to distribute the weight
- Keep your weight down to avoid putting extra stress on your joints
- Relax your muscles to reduce the pain
American College of Rheumatology http://www.rheumatology.org
National Institute of Arthritis and Musculoskeletal and Skin Diseases http://www.niams.nih.gov
The Arthritis Foundation http://www.arthritis.org
BC Health Guide, British Columbia Ministry of Health http://www.bchealthguide.org
The Arthritis Society http://www.arthritis.ca
Beers MH, Berkow R.Calcium pyrophosphate dihydrate crystal deposition disease (Pseudogout). The Merck Manual of Diagnosis and Therapy. Section 5, Chapter 55, Crystal-Induced Conditions. The Merck Manual website. Available at: http://www.merck.com/mrkshared/mmanual/section5/chapter55/55c.jsp. Accessed September 12, 2005.
Calcium pyrophosphate dihydrate crystal deposition disease (CPPD) (Pseudogout). The Arthritis Foundation website. Available at: http://www.arthritis.org/conditions-treatments/disease-center/calcium-pyrophosphate-dihydrate-crystal-deposition-disease-cppd-pseudo-gout/. Accessed September 12, 2005.
Pseudogout. American College of Rheumatology website. Available at: http://www.rheumatology.org/public/factsheets/pseudogout%5Fnew.asp?aud=pat . Accessed September 12, 2005.
Pseudogout. Mayo Clinic website. Available at: http://www.mayoclinic.com/invoke.cfm?objectid=40938B02-101F-43C1-8B895B005C6E0B2C. Accessed September 12, 2005.
Tenenbaum J. Inflammatory musculoskeletal conditions in older adults. Geriatrics Aging. 2005; 8(3):14-17.
What you need to know about pseudogout. Cleveland Clinic website. Available at: http://www.clevelandclinic.org/arthritis/treat/facts/pseudogout.htm. Accessed on September 12, 2005.
- Reviewer: Lawrence Frisch, MD, MPH
- Review Date: 09/2011 -
- Update Date: 09/20/2011 -
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
Copyright © EBSCO Publishing
All rights reserved.