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Clot Risk High for Pregnant Women in Hospital

Clot Risk High for Pregnant Women in Hospital

Risk higher during third trimester and for older women

FRIDAY, Nov. 8 (HealthDay News) -- Pregnant women admitted to the hospital for reasons other than delivery or venous thromboembolism are at higher risk of a first venous thromboembolism, particularly during the third trimester and among older women, according to a study published online Nov. 7 in BMJ.

Alyshah Abdul Sultan, from the University of Nottingham in the United Kingdom, and colleagues assessed the risk of first venous thromboembolism among 206,785 women (15 to 44 years old) who had at least one pregnancy between 1997 and 2010 and who were admitted to the hospital for at least one day for reasons other than delivery or venous thromboembolism.

The researchers found that, after adjusting for a number of factors, women admitted to the hospital during pregnancy were at higher risk of venous thromboembolism (incidence rate ratio, 17.5). There was also an increased risk in the 28 days after discharge (incidence rate ratio, 6.27). The rate of venous thromboembolism during and after admission was highest during the third trimester and among women 35 years and older.

"The overall risk of first venous thromboembolism in pregnant women increased during admissions to hospital not related to delivery, and remained significantly higher in the 28 days after discharge," Sultan and colleagues conclude.

One author disclosed financial ties to the pharmaceutical industry.

Full Text (http://www.bmj.com/content/347/bmj.f6099 )