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Early Baldness Ups Prostate CA Risk for African-Americans

Early Baldness Ups Prostate CA Risk for African-Americans

Frontal baldness tied to increased odds of high-stage, high-grade cancer, especially for younger men

TUESDAY, March 26 (HealthDay News) -- For African-Americans, who are at elevated prostate cancer risk, baldness at age 30 correlates with prostate cancer, with frontal baldness linked to increased odds of high-stage and high-grade disease, according to a study published online March 26 in Cancer Epidemiology, Biomarkers & Prevention.

Charnita Zeigler-Johnson, Ph.D., from the University of Pennsylvania School of Medicine in Philadelphia, and colleagues recruited 318 African-American prostate cancer cases and 219 African-American controls to examine the correlation between early-onset baldness with prostate cancer.

The researchers found that baldness correlated with increased likelihood of prostate cancer (odds ratio [OR], 1.69). Frontal baldness correlated with increased odds of high-stage (OR, 2.61) and high-grade (OR, 2.20) tumors, with a stronger correlation for men diagnosed before the age of 60 years (OR, 6.51 and 4.23, respectively). There was a suggested interaction for smoking, median age, and any baldness.

"African-American men present with unique risk factors including baldness patterns that may contribute to prostate cancer disparities," the authors write.

Abstract (http://cebp.aacrjournals.org/content/early/2013/03/22/1055-9965.EPI-12-0944.abstract )Full Text (subscription or payment may be required) (http://cebp.aacrjournals.org/content/early/2013/03/22/1055-9965.EPI-12-0944.full.pdf+html )