Choline has only recently been recognized as an essential nutrient. Choline is part of the neurotransmitter acetylcholine, which plays a major role in the brain; for this reason, many studies have been designed to look at choline's role in brain function.
According to US and Canadian guidelines, the recommended daily intake of choline is as follows:
- 0-6 months: 125 mg
- 7-12 months: 150 mg
- 1-3 years: 200 mg
- 4-8 years: 250 mg
- 9-13 years: 375 mg
- 14 years and older: 550 mg
- 14-18 years: 400 mg
- 19 years and older: 425 mg
- Pregnant Women : 450 mg
- Nursing Women : 550 mg
Most studies of choline as a treatment for diseases have used between 1-30 g of choline or choline-containing supplements per day. This wide range is due to the existence of several different types of choline supplements, all with varying amounts of the active ingredient.
What Is the Scientific Evidence for Choline?
The tolerable upper intake of choline has been set at 3.5 g daily for adults. Tolerable upper intake is defined as: the highest daily intake over a prolonged time known to pose no risks to most members of a healthy population.
In higher dosages, minor but annoying side effects may occur, such as abdominal discomfort, diarrhea, and nausea. Maximum safe dosages for young children, pregnant or nursing women, or those with severe liver or kidney disease have not been determined.
- Reviewer: EBSCO CAM Review Board
- Review Date: 08/2013 -
- Update Date: 08/22/2013 -