These drugs are the most powerful medications for reducing stomach acid levels; in fact, they almost completely shut down the stomach's ability to produce acid. (Their science fiction–sounding name comes from the last stage of the acid-secreting process, called the "proton pump.") Proton pump inhibitors are used for ulcers as well as for the treatment of moderate to severe esophageal reflux, commonly known as heartburn.
Drugs in this family include lansoprazole (Prevacid), omeprazole (Prilosec), and others.
The herb St. John's wort is known to interact with numerous drugs. There are two potential harmful interactions between St. John's wort and proton pump inhibitors.
Vitamin B 12 deficiency is a concern with the use of all drugs that reduce stomach acidity.
In food, vitamin B 12 is always accompanied by proteins, and it must be separated from them before it can begin to be absorbed. Following separation, B 12 is then attached to a substance called intrinsic factor, which allows B 12 to be absorbed in the intestines.
- Reviewer: EBSCO CAM Review Board
- Review Date: 08/2013 -
- Update Date: 08/22/2013 -